产品描述

VER 155008是新型的腺苷衍生的HSP70抑制剂，IC50为0.5 μM。

靶点

IC50

体外研究

VER-155002 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). The compound inhibits proliferation of several colon and breast cancer cell lines, induces caspase dependent apoptosis in BT474 cells and down regulates expression of Her2 and Raf-1 in HCT116 cells.

体内研究

溶解性

DMSO >10 mg/mL

稳定性

2年 -20°C粉状，6月-80°C溶于DMSO

特征