JBScreen Detergents-MiTeGen蛋白结晶去污剂

JBScreen Detergents-MiTeGen蛋白结晶去污剂

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JBScreen Detergents

The JBScreen Detergents can be used throughout the protein purification process or can be added afterwards by dialysis or ion-exchange chromatography (detergent exchange). Detergent exchange can be vital for obtaining well-diffracting membrane-protein crystals [1].

JBScreen 洗涤剂
JBScreen 去污剂可以在整个蛋白质纯化过程中使用,也可以在之后通过透析或离子交换层析(去污剂交换)添加。 去污剂交换对于获得衍射良好的膜蛋白晶体至关重要 [1]。

Full Description

 

JBScreen Detergents SKU: M-CS-521 $215.00
JBScreen Detergents SKU: M-CS-522 $215.00
JBScreen Detergents SKU: M-CS-523 $215.00
JBScreen Detergents SKU: M-CS-524 $215.00
JBScreen Detergents SKU: M-CS-525 $645.00
JBScreen Detergents SKU: M-CS-308 $1,807.00

Categories: Crystallization Optimization, Membrane Protein Crystal Screens, Membrane Protein Crystallization

Product Information

  • Product Description
  • Product Specification

The JBScreen Detergents contain 4x 24 unique detergents that are compatible with most common crystallization reagents and are therefore perfectly suited for membrane protein solubilization:

  • Ionic detergents
  • Non-ionic detergents
  • Zwitterionic detergents
  • Non-detergent Sulfobetaines
  • Synthetic Lipids

The JBScreen Detergentscan be used throughout the protein purification process or can be added afterwards by dialysis or ion-exchange chromatography (detergent exchange). Detergent exchange can be vital for obtaining well-diffracting membrane-protein crystals [1].

JBScreen Detergents are also valuable for additive screening with detergents and detergent mixtures [2,3] in combination with the JBScreen Membrane. This combination will enable you to screen a broad range of crystallization conditions, while concentrating on the most successful detergents – and therefore making crystallization screening of membrane proteins much more efficient and less time consuming.

类别:结晶优化, 膜蛋白晶体筛选, 膜蛋白结晶
产品信息
产品描述
产品规格
JBScreen 去污剂包含 4x 24 种独特的去污剂,可与最常见的结晶试剂兼容,因此非常适合膜蛋白溶解:
离子洗涤剂
非离子洗涤剂
两性离子洗涤剂
非洗涤剂磺基甜菜碱
合成脂质
JBScreen Detergent 可以在整个蛋白质纯化过程中使用,也可以在之后通过透析或离子交换层析(去垢剂交换)添加。去污剂交换对于获得衍射良好的膜蛋白晶体至关重要 [1]。

JBScreen 去污剂与 JBScreen 膜结合使用,也可用于对去污剂和去污剂混合物进行添加剂筛选 [2,3]。这种组合将使您能够筛选广泛的结晶条件,同时专注于最成功的去污剂——从而使膜蛋白的结晶筛选更加高效和耗时更少。

References:
[1] Rosenow et al. (2003) The influence of detergents and amphiphiles on the solubility of the light harvesting complex. Acta Cryst. D59:1422
[2] Adir (1999) Crystallization of the oxygen-evolving reaction centre of photosystem II in nine different detergent mixtures. Acta Cryst. D55:891
[3] Koronakis et al. (2000) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature 405:914

Download technical sheet from below:JBScreen Detergents HTS JBScreen Detergents 1 JBScreen Detergents 2 JBScreen Detergents 3 JBScreen Detergents 4

For additional questions please call +1 607 266 877 or email [email protected]