Recombinant enzyme prepared from insect cells infected with baculovirus containing human FMO3 cDNAs

FMO3 is the major human hepatic FMO form. FMO3 can N- and S-oxidize several nucleophilic nitrogen- and sulfur-containing drugs and chemicals. For example: the stereoselective (S)-nicotine N-1′-oxygenation, cimetidine S-oxygenation, and the N-oxygenation of clozapine. Trimethylaminuria, a human disorder characterized by an impaired ability to convert malodorous trimethylamine to its odorless N-oxide, is most likely caused by a genetic polymorphism in the human FMO3 gene.

Available size: 0.5 mL

Protein concentration: 5 mg/ mL

Product Number

456233

Qty./Pk

1?/ Pk

Qty./Cs

1?/ Ea

Brand

Corning?

Size

0.5 mL

Species

Human

Enzyme Type

FMO

Protein Concentration

5 mg/mL

Storage

-80 C

Cellular Location

Microsome