Corning? Supersomes? Human CYP2C19 + Oxidoreductase + b5, 0.5 nmol Recombinant enzyme prepared from insect cells infected with baculovirus containing desired cDNAs

CYP2C19 metabolizes 5-10% of prescribed medications. CYP2C19 drug substrates include omeprazole, lansoprazole, pantoprazole, phenytoin, diazepam, and S-mephenytoin (4 -hydroxylation, probe substrate/activity). CYP2C19 is responsible for the (S)-mephenytoin 4 -hydroxylase polymorphism. Approximately 20% of Asians are deficient in CYP2C19 activity (due to two prevalent allelic variants: *2 and *3, which result in inactive protein.

Contains Human Oxidoreductase and cytochrome b?

Available size: 0.5 nmole P450 in 0.5 mL

Protein concentration: Available in batch data sheet. Contact Corning Scientific support to obtain the information.

Product Number

456259

Qty./Pk

1?/ Pk

Qty./Cs

1?/ Ea

Brand

Corning?

Size

0.5 nmol

Species

Human

Enzyme Type

P450

Protein Concentration

Lot-dependent

Storage

-80 C

Cellular Location

Microsome