Discontinued: 452227; Suggested Replacement: None.
This kit contains separate vials of matching human liver microtomes, cytosol, and S9. All fractions are isolated from the same 50 donors. The kit is designed to improve predictions and scaling by minimizing metabolizing enzymes donor variability. The kit is suitable for metabolic stability testing, metabolite identification, reaction phenotyping, and inhibition testing.
Features/Benefits:
Pools of 50 donors with an equal donor mix on a per milligram microsomal protein basis
Minimized donor variability with improved prediction and scaling
Characterized for many important cytochrome P450, UGTs and other enzymes.
Tissues are sourced from US-based Organ Procurement Organizations, meeting high ethical standards with strict traceability
Manufactured by adhering to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human T-cell leukemia virus) pathogens, and CMV (cytomegalovirus)
Kit Content: 1 EA of HLM (0.5 mL), S9 (1.0 mL) and cytosol (1.0 mL)
Protein Concentration: 20 mg/ mL in 250 mM Sucrose
Shelf life: N/A (this product is stable for more than 10 years when stored properly)
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1 Kit
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20 mg/mL
-80 C
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