This S9 product is targeted to meet a calculated mean of the average liver profile for the big 5 CYPs based on ~140 tested livers for improved prediction and scaling for these 5 enzymes (CYP1A2, 2C9, 2C19, 2D6, and 3A4). S9 from pre-selected donors are mixed at ratios to give the desired activities for the big 5 P450s. The product is also characterized for other important metabolizing CYP enzymes
Features/Benefits:
Pool of ~20 pre-selected donors mixed at ratios to give the desired activities for the big five P450s (CYP1A2, 2C9, 2C19, 2D6, and 3A4)
The activities for the big five P450s are targeted to meet a calculated mean of the average liver profile based on ~140 tested livers for improved prediction and scaling for these 5 enzymes
Characterized for additional important cytochrome P450 enzymes.
Large lot size available
Tissues are sourced from US-based Organ Procurement Organizations, meeting high ethical standards with strict traceability
Manufactured by adhering to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human T-cell leukemia virus) pathogens, and CMV (cytomegalovirus)
Available Size: 1.0 mL
Protein Concentration: 20 mg/ mL in 250 mM Sucrose
Shelf life: N/A (this product is stable for more than 10 years when stored properly)
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452961
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1 mL
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20 mg/mL
-80 C
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