盐酸左旋咪唑；Levamisole HCl
分子式：C11H12N2S.HCl 分子量：240.75
简介：Levamisole ((-)-Tetramisole) hydrochloride 是驱虫剂和免疫调节剂。Levamisole hydrochloride 对 HSV 病毒显具有显着的抗病毒作用。
物理性状及指标：
外观：……………………粉末
溶解性：…………………H2O : 40 mg/mL ；DMSO : 15.5 mg/mL (64.38 mM; Need ultrasonic and warming)；Ethanol : 12.5 mg/mL (51.92 mM; Need ultrasonic)
含量：……………………>98%
储存条件：常温，避光防潮密闭干燥
运输条件：常温运输
生物活性
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产品描述 |
Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV. |
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靶点 |
Parasite HSV-1 |
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体外研究 |
Levamisole suppresses the production of white blood cells, resulting in neutropenia and agranulocytosis. With the increasing use of levamisole as an adulterant, a number of these complications have been reported among cocaine users [1] [2]. Levamisole reversibly and noncompetitively inhibits most isoforms of alkaline phosphatase (e.g., human liver, bone, kidney, and spleen) except the intestinal and placental isoform [3]. It is thus used as an inhibitor along with substrate to reduce background alkaline phosphatase activity in biomedical assays involving detection signal amplification by intestinal alkaline phosphatase, for example in in situ hybridization or Western blot protocols. It is used to immobilize the nematode C. elegans on glass slides for imaging. |
用途及描述：科研试剂，广泛应用于分子生物学，药理学等科研方面，严禁用于人体。
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TESTS |
SPECIFICATIONS |
Appearance |
White acicular crystal powder |
Solubility |
40mg/ml water , clear |
Identification |
HNMR |
pH |
3.5～5.0 |
Specific rotation |
>-121.5° |
Purity(HPLC) |
>98% |