JBS Floppy-Choppy-MiTeGen用于难以结晶的蛋白质的救援套装

JBS Floppy-Choppy-MiTeGen用于难以结晶的蛋白质的救援套装

上海金畔生物代理MiTeGen品牌蛋白结晶试剂耗材工具等,我们将竭诚为您服务,欢迎访问MiTeGen官网或者咨询我们获取更多相关MiTeGen品牌产品信息。JBS Floppy-Choppy

JBS Floppy-Choppy

The JBS Floppy-Choppy is the rescue kit for proteins which are recalcitrant to crystallization. It enables the researcher to modify the protein target by in situ proteolysis to improve its crystallization behavior.

JBS Floppy-Choppy

JBS Floppy-Choppy 是用于难以结晶的蛋白质的救援套件。 它使研究人员能够通过原位蛋白水解来修饰蛋白质目标,以改善其结晶行为。

SKU: M-CO-110Category: Crystallization Optimization

Product Information

  • Product Description
  • Product Specification

The JBS Floppy-Choppy is the rescue kit for proteins which are recalcitrant to crystallization. It enables the researcher to modify the protein target by in situ proteolysis to improve its crystallization behavior.The method implies the addition of trace amounts of protease to the protein solution immediately prior to crystallization. Thus, the crystallization experiment is very straightforward. It can be set up without evaluating the efficacy of proteolysis, without stopping the proteolysis reaction and without purification of any proteolyzed protein fragments

In situ proteolysis is one of the most efficacious crystallization rescue strategies used at structural genomic centers [1,2].

[1] Dong et al. (2007) In situ proteolysis for protein crystallization and structure determination.Nature Methods 4:1019.

[2] Wernimont et al. (2009) In situ Proteolysis to Generate Crystals for Structure Determination: An Update. PLoS ONE 4: e5094

Download technical sheet from below:
JBS Floppy-Choppy, 1 kitFor additional questions please call +1 607 266 877 or email [email protected]