标签归档：Crystallization Screens

Morpheus Additive Screen,MiTeGen蛋白结晶,M-MD1-93,Crystallization Screens

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Morpheus Additive Screen

Morpheus Additive Screen

MD1-93 在箔密封板中以 96 x 100 uL 条件呈现。

Morpheus 添加剂筛选是一种新的 96 条件添加剂筛选，包含适用于可溶性和膜蛋白的广泛配体库。

  • Manufacturers SKU: MD1-93
  • MiTeGen SKU: M-MD1-93

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SKU: M-MD1-93Category: Crystallization Screens

Product Information

  • Features
  • Resources

Features of the Morpheus Additive Screen:

  • Contains all the compounds from the successful Morpheus and Morpheus II screens.
  • Test a large range of precipitants, stabilizers, buffers, nucleants, phasing compounds, cryoprotectants and surfactants all in one screen.
  • Enhance stability and solubility of protein for crystallization with the inclusion of NDSBs, polyamines, monosaccharides and amino acids.
  • Contains heavy atoms as additives for experimental phasing.
  • Use in protein stability screen assays e.g. thermal shift assays.
  • Suitable for both soluble and membrane proteins.

Morpheus II FX-96-MiTeGen蛋白结晶,M-MD1-92-FX,Crystallization Screens

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Morpheus II FX-96

Morpheus II FX-96

MD1-92-FX is presented as 96 x 100 uL conditions.

Morpheus II 经过优化，可产生传统屏幕中未观察到的晶体，还包括用于实验定相的重原子以及用于冷冻保护的多元醇。

  • Manufacturers SKU: MD1-92-FX
  • MiTeGen SKU: M-MD1-92-FX

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SKU: M-MD1-92-FXCategory: Crystallization Screens

Product Information

  • Features
  • Resources

Features of Morpheus II:

  • Targeted incorporation of 35 low-molecular weight PDB ligands into 96 conditions.
  • Incorporation of heavy atoms as additives for experimental phasing.
  • Suitable for membrane proteins with PEGS and polyols as main precipitants.
  • The inclusion of NDSBs, polyamines, amino acids and monosaccharides to enhance solubility and stability of many proteins for crystallization.
  • New polyols included for cryoprotection of conditions: no need to investigate more conditions for cryo-cooling.
  • Innovative buffer systems facilitate pH optimization.
  • Readily available Morpheus II Optimization reagents including the Mixes and Stock reagents.
  • 将 35 种低分子量 PDB 配体靶向结合到 96 种条件中。
    加入重原子作为实验定相的添加剂。
    适用于以 PEGS 和多元醇为主要沉淀剂的膜蛋白。
    加入 NDSB、多胺、氨基酸和单糖，以提高许多蛋白质的溶解度和稳定性以进行结晶。
    包括用于低温保护条件的新多元醇：无需研究更多低温冷却条件。
    创新的缓冲系统有助于优化 pH 值。
    现成的 Morpheus II 优化试剂，包括 Mixes 和 Stock 试剂。

Morpheus II,MiTeGen蛋白结晶,M-MD1-91,Crystallization Screens

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Morpheus II

Morpheus II

MD1-91 以 96 x 10 毫升的条件呈现（包括 12 x 15 毫升的玻璃瓶，其中装有与水混合的多胺粉末）。

Morpheus II 经过优化，可产生传统屏幕中未观察到的晶体，还包括用于实验定相的重原子以及用于冷冻保护的多元醇。

SKU: M-MD1-91Category: Crystallization Screens

Product Information

  • CX100 Specifications
  • CX100 Features
  • CX100 Accessories
  • Static Holding Days: 22
  • Working Time Days: 17
  • Evaporation Rate: 0.19 liters per days
  • Liquid Nitrogen Adsorbed: 4.1 liters
  • Weight Empty: 11.7 lbs / 5.3 kg
  • Weight Full: 19 lbs. / 8.6 kg
  • Neck Diameter: 2.78″ / 71mm
  • Overall Height: 18.4″ / 467mm
  • Overall Diameter: 9.2″ / 234mm
  • No. of Canisters: 1
  • Canister Dimensions: 2.64″ x 11″ / 67 x 279mm
  • Canister Material: Thin gauge stainless steel
  • No. of 1.2ml & 2.0ml Vials (5/cane): 85
  • No. of 1.2ml & 2.0ml Vials (6/cane): 102
  • No. of 1/2 Straws (10/cane): 280
  • No. of 1/2 cc Straws – Bulk (2 levels): 800
  • ICBiomedical has purchased the Worthington Industries line of cryogenic equipment.
  • ICBiomedical SKU: 366550
  • MiTeGen SKU: TW-CX100
  • Worthington Industries SKU: 366550
  • Taylor Wharton SKU: CX100B-11M

Shipping Case For CX100 or CXR100

Morpheus II
Square shipping case for CX100 & CXR100 dry shippers. Features a thick hard plastic shell with padded…

Lightweight Shipping Case for CX100 or CXR100 Polyethylene

Morpheus II
Lightweight Shipping Case for CX100 or CXR100. Constructed of Polypropylene w/ Steel Nickel-Plated loops….

Upright Shipping Case For 4D 4DX CX100 and CXR100

Morpheus II
Mushroom designed upright shipping case for the IC Biomedical 4D, 4DX, CX100 and CXR100 dry shippers.

Necktube Core For CX100

Morpheus II
Replaceable necktube core for CX100

The Cryo Combination,MiTeGen蛋白结晶,M-MD1-94,Crystallization Screens

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The Cryo Combination

The Cryo Combination

Purchase both CryoProtX and CryoSol together.

CryoProtX™
Get more from your crystals from our multi-component cryoprotectant kits for protein crystals. This kit is designed for the cryoprotection of protein crystals and is for use after the crystals have been grown. They can offer cryopreservation equivalent to 40% glycerol, without the worry of dissolving the crystal.

从我们用于蛋白质晶体的多组分冷冻保护剂套件中获取更多晶体。 该试剂盒专为蛋白质晶体的冷冻保护而设计，可在晶体生长后使用。 他们可以提供相当于 40% 甘油的冷冻保存，而无需担心晶体溶解。

CryoSol™
CryoSol™ is an extended set of multicomponent solutions intended for crystal cryoprotection and soaking of hydrophobic ligands into crystals.

  • Manufacturers SKU: MD1-94
  • MiTeGen SKU: M-MD1-94

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SKU: M-MD1-94Category: Crystallization Screens

MiTeGen品牌产品,CryoSol,MiTeGen蛋白结晶,MiTeGen M-MD1-90,Crystallization Screens

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CryoSol

CryoSol

MD1-90 呈现为 33 x 1.5 mL 微管。
一组多组分溶液，用于将疏水性配体溶解/浸泡到晶体中并随后进行晶体冷冻保护。

  • Manufacturers SKU: D1-76
  • MiTeGen SKU: M-MD1-76

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SKU: M-MD1-90Category: Crystallization Screens

Product Information

  • Features
  • CX100 Features

Features of CryoSol:

  • Solubilization of hydrophobic ligands.
  • Easily prepare ligand-loaded cryosolutions for soaking experiments.
  • Co-crystallization screening of protein-ligand complexes.
  • Protein friendly mixes of Dimethyl sulfoxide (DMSO/dioxane/ethylene glycol should improve ligand solubilization).
  • Contains 2,3-butanediol- compatible with enzymatic activity.

CryoProtX,MiTeGen蛋白结晶,M-MD1-61,Crystallization Screens

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CryoProtX

CryoProtX

MD1-61 is presented as a 46 x 1.5 mL kit

该试剂盒专为蛋白质晶体的冷冻保护而设计，可在晶体生长后使用。 使用这款易于使用的预混合冷冻试剂盒，充分利用您的蛋白质晶体。

  • Manufacturers SKU: MD1-61
  • MiTeGen SKU: M-MD1-61

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SKU: M-MD1-61Category: Crystallization Screens

Morpheus Fusion HT-96,MiTeGen蛋白结晶,MiTeGen M-MD1-130,Crystallization Screens

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Morpheus Fusion HT-96

Morpheus Fusion HT-96

Morpheus® Fusion 是一种 96 条件不完全因子蛋白质结晶筛选，包含一系列低分子量配体。 解锁以前使用传统屏幕无法访问的新型化学空间。 条件的化学性质可以被认为是“温和的”，因为它们由基于 PEG 的沉淀剂混合物制成，并且没有极端的 pH 值。

因此，FUSION 几乎适用于具有挑战性稳定性的样品（包括大分子复合物和膜蛋白）以及用药物化合物浸泡所得晶体。

SKU: M-MD1-130Category: Crystallization Screens

Product Information

  • Features
  • CX100 Features

Features of Morpheus® Fusion:

  • Incomplete Factorial design covering a range of pH, precipitants, PEGs and salt additives.
  • 19 Additive mixes integrating all reagents from MORPHEUS I, most reagents from Morpheus II and some from Morpheus III
  • Suitable for membrane proteins with PEGS and polyols as main precipitants.
  • Morpheus® ligands promote initial crystal formation and lattice stability.
  • Reduced crystal “stress” – all conditions are cryoprotected*.
  • Easy optimization of ‘hits’.
  • Readily available Morpheus® Fusion Optimization reagents including the Mixes and Stock reagents.

 

Morpheus HT-96 Green Screen,MiTeGen蛋白结晶,M-MD1-47-GREEN,Crystallization Screens

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Morpheus HT-96 Green Screen

Morpheus HT-96 Green Screen

M-MD1-47-GREEN 呈现为 96 x 1 mL 条件。 Green Screens 含有一种非共价荧光染料，当用紫外光照射时，它会在大多数蛋白质上传递荧光。 这不仅增加了信噪比（对于非常小的晶体很重要），而且还允许识别缺乏内在荧光的蛋白质晶体，否则这些晶体会保持模糊。

  • Manufacturers SKU: MD1-47-GREEN
  • MiTeGen SKU: M-MD1-47-GREEN
SKU: M-MD1-47-GREENCategory: Crystallization Screens

Product Information

  • Features
  • Resources

Features of Morpheus:

  • Simple and effective 3D grid design covering a range of pH, PEGs and salt additives.
  • 49 low molecular weight ligands promote both initial crystal formation and lattice stability.
  • Ideal for membrane proteins (contains PEGs and low salt).
  • Reduced crystal “stress” – all conditions are cryo-protected.
  • Derived from extensive data mining of over 33,000 PDB entries.

Ligand-Friendly Screen,MiTeGen蛋白结晶,Crystallization Screens

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Ligand-Friendly Screen
Ligand-Friendly Screen

Ligand-Friendly Screen

自 2004 年以来，配体友好筛选 (LFS)4 一直是牛津结构基因组学联盟 (SGC) 的两个主要粗筛选之一； 据最新统计，它在 10 年中生产了 190 种新颖的结构。 LFS 在 Ng, J. T. et al, 20153 中进行了描述。由创建成功 BCS 屏幕的同一组在牛津的 SGC 开发，该团队于去年推出并基于由珍妮特纽曼在协作结晶中心创建的流行 PACT 屏幕4， CSIRO。

Learn More About This Product
 Ligand-Friendly Screen SKU: M-MD1-127 $1,056.00
Ligand-Friendly Screen SKU: M-MD1-128 $400.50
Ligand-Friendly Screen SKU: M-MD1-121 $478.50
Ligand-Friendly Screen SKU: M-MD1-121-ECO $478.50
Ligand-Friendly Screen SKU: M-MD1-122 $228.00
Ligand-Friendly Screen SKU: M-MD1-122-ECO $228.00
Ligand-Friendly Screen SKU: M-MD1-122-FX $34.50

Category: Crystallization Screens

Product Information

Key Features:

  • Identify more tight-binding ligands, as it contains no components that are likely to bind at protein-ligand interaction sites.
  • Near physiological pH conditions ensure you are studying the active form of your protein.
  • More hits for rarely-crystallising proteins. The semi-systematic format of the screen provides multiple trials of similar conditions – an important factor for difficult cases.
  • Increased hit rate for ligand co-crystallisations – the semi-systematic format efficiently screens around related conditions when complex formation alters crystallisation conditions.
  • In use at the SGC for more than 10 years, crystals grown in the screen conditions have resulted in 190 structures so far, including those of Haspin and CLK3 in recent publications.

NextGen Combo HT-96 – MD1-89 SG1 and MD1-122 The LFS,MiTeGen蛋白结晶,M-MD1-128,Crystallization Screens

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NextGen Combo HT-96 – MD1-89 SG1 and MD1-122 The LFS

NextGen Combo HT-96 – MD1-89 SG1 and MD1-122 The LFS

MD1-128 is presented as 192 x 1 mL conditions.

A combination of SG1 Screen HT-96 (M-MD1-89) & Ligand-Friendly Screen HT-96 (M-MD1-122).

SKU: M-MD1-128Category: Crystallization Screens